Generating the Tick Interrupt

I have equation I am working now in project that needs to reduce the generation tick interrupt.
I am using ATMega128.
My equation is:  if I use the time counter0 Rather than time counter1. It will be work or will be appear more problem
What is the Advantage and disadvantage for that? Thank for your answer. regards,
Mody

Generating the Tick Interrupt

Normally you can use any convenient timer peripheral to generate a tick.